VISDB Viral Integration Site DataBase

VIS ID

TVIS10011147

Fusion event

HBV-CADPS2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1961

Orient

+

Integrated sequence

CTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCC| |TTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACT

Chromosome

chr7

Cytoband

q31.32

Reference genome

Start

End

122258978/122618924 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-30c-5p ; hsa-mir-1256 ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-3127-3p ; hsa-mir-3679-3p ; hsa-mir-4262 ; hsa-mir-4642 ; hsa-mir-506-5p ; hsa-mir-5684 ; hsa-mir-6756-3p ; hsa-mir-6826-3p ; hsa-mir-6832-3p

Nearest miRNA

hsa-mir-10525/Upstream/5598605; hsa-mir-10399/Downstream/4439164;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/301637, chr7-CpG: 120/Downstream/266770

Upstream sequence

ACCAGGGCCACTCGGCCTGGCGTCTGGAGCACTGGCGGCATCGGCGACCACAGCCTCTAGAGACAAAGTTCTGTAGTGCACTGACTTCTATCATACTCAG

Downstream sequence

TATGGTAGGAAAATATCTGCCTTAGATAGACATAGCAACAGAGGATGTCAAAACAATTTTATAAATATGCAAACTTCTCAGACCATGCAAAGTGAAGTTT