VISDB Viral Integration Site DataBase

VIS ID

TVIS10011148

Fusion event

HBV-CADPS2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2533

Orient

+

Integrated sequence

TCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAA| |ACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAAT

Chromosome

chr7

Cytoband

q31.32

Reference genome

Start

End

122258980/122618926 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-30c-5p ; hsa-mir-1256 ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-3127-3p ; hsa-mir-3679-3p ; hsa-mir-4262 ; hsa-mir-4642 ; hsa-mir-506-5p ; hsa-mir-5684 ; hsa-mir-6756-3p ; hsa-mir-6826-3p ; hsa-mir-6832-3p

Nearest miRNA

hsa-mir-10525/Upstream/5598607; hsa-mir-10399/Downstream/4439162;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/301639, chr7-CpG: 120/Downstream/266768

Upstream sequence

GTTGTATAGTAAAATGTGTTCAATTACTCACCTCCTCAAACTATGAGCATACATAATTTTGAGTAAAACAAAAAGTAAAATTTTTAAATGTCATGTATCA

Downstream sequence

TGGTAGGAAAATATCTGCCTTAGATAGACATAGCAACAGAGGATGTCAAAACAATTTTATAAATATGCAAACTTCTCAGACCATGCAAAGTGAAGTTTTA