Basic Information
VIS ID
TVIS10011151
Fusion event
HBV-chr8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1791
Orient
-
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCA| |TAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
End
78899602/77987367 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/1020517; hsa-mir-10400/Downstream/1344821;
Nearby gene
PEX2(-986322) ; PKIA(+528734) ;
Upstream sequence
TCAGGTGTCAGGTGTGCTAGTCTTGAGAAGAACTATCCTCAGAGCAGAATTTAATACACTGTTGGGTGGCAATTAGATAATCACATCTACCCAGCAAGGA
Downstream sequence
CCCCAGTCCTACTTTGGCATCTGTCTCCCTAGTTTCTTCATCATTTGATGTCACTTTATCAGGCACTCTGCTAGGTCTGTAAATTAAACTTCTTGAAACA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate