VISDB Viral Integration Site DataBase

VIS ID

TVIS10011156

Fusion event

HBV-ZBTB10 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1801

Orient

-

Integrated sequence

GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG

Chromosome

chr8

Cytoband

q21.13

Reference genome

Start

End

81435029/80522794 (Hg38)

Orient

+

Location type

downstream

Target gene

miRNAs that regulate target gene

hsa-mir-27a-3p ; hsa-mir-335-5p ; hsa-mir-29c-3p ; hsa-mir-125a-5p ; hsa-mir-215-5p ; hsa-mir-10a-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-877-3p ; hsa-mir-425-5p ; hsa-mir-23a-3p ; hsa-mir-4662a-5p ; hsa-mir-6831-3p ; hsa-mir-3651 ; hsa-mir-4762-5p ; hsa-mir-548c-3p ; hsa-mir-3658 ; hsa-mir-3653-3p ; hsa-mir-4480 ; hsa-mir-3691-3p ; hsa-mir-4495 ; hsa-mir-6507-5p ; hsa-mir-3682-5p ; hsa-mir-374a-3p ; hsa-mir-298 ; hsa-mir-922 ; hsa-mir-2115-3p ; hsa-mir-10b-3p ; hsa-mir-2278 ; hsa-mir-548at-5p ; hsa-mir-361-5p ; hsa-mir-195-5p ; hsa-mir-497-5p ; hsa-mir-16-5p ; hsa-mir-424-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-6838-5p ; hsa-mir-4799-5p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-362-5p ; hsa-mir-500b-5p ; hsa-mir-1224-5p ; hsa-mir-4668-5p ; hsa-mir-7856-5p ; hsa-mir-587 ; hsa-mir-3148 ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-873-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6165 ; hsa-mir-6715b-3p ; hsa-mir-299-5p ; hsa-mir-215-3p ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-6715a-3p ; hsa-mir-551b-5p

Nearest miRNA

hsa-mir-12123/Upstream/281321; hsa-mir-10400/Downstream/10682691;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/35425, chr8-CpG: 92/Downstream/55231

Upstream sequence

ATACATTTTAAAAGATATTTTGAAACAAACTTTGAGCACTTCTAGTGGTTGTTATTGGTTGGCCAAGGCAGGGAAACCAATTTGCCAAGAAAAAAAAAAC

Downstream sequence

AAGGAGAAAATAGGAAATGAAAGGATTAGGACTTGGGCATTTATATTAATACAAAATGGTGTAAACGGCCTGAATATCACTGTAGTAGTATCATACGGGG