VISDB Viral Integration Site DataBase

VIS ID

TVIS10011158

Fusion event

HBV-CNTLN integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2725

Orient

+

Integrated sequence

ATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAAT| |CATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCAT

Chromosome

chr9

Cytoband

p22.2

Reference genome

Start

End

17166463/17166465 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-10a-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-222-5p ; hsa-mir-545-5p ; hsa-mir-548m ; hsa-mir-329-5p ; hsa-mir-15b-3p ; hsa-mir-3122 ; hsa-mir-3913-5p ; hsa-mir-450a-1-3p ; hsa-mir-6513-5p ; hsa-mir-6716-5p ; hsa-mir-887-5p ; hsa-mir-3672 ; hsa-mir-6818-3p ; hsa-mir-6864-3p

Nearest miRNA

hsa-mir-101-2/Upstream/11158561; hsa-let-7a-1/Downstream/1406841;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/30757, chr9-CpG: 120/Downstream/412258

Upstream sequence

AAGTTGAAACAACAGGATTTCAGAAAAAATTGAGCAAGGGAACTCCCCAGGTCTAAAGATCATTTTTATATCCCTCCCCTTGCCAGCTGCTAAAACACCT

Downstream sequence

tcaaattcaggctcaggagtttaggattgaaagcatccattgattgtccagcacaaagaactattgcaaggcacattattatgcaattttagaatgttgg