Basic Information
VIS ID
TVIS10011161
Fusion event
HBV-chrY integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2202
Orient
+
Integrated sequence
TCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTC| |TTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGAC
Host Sequence
Chromosome
chrY
Cytoband
q11.223
Reference genome
End
22469960/20308074 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/6828808;
Nearby gene
KDM5D(-563135) ; TTTY10(+157594) ;
Upstream sequence
ttccattccattccattccattccattccattccattgcattccattccattccattcctttgcactgcactccattccattacattctactctatCTGA
Downstream sequence
aaggtgttatatccagagattgttccttcagatgtgtccagagtttcttccttctgtccggttcacggtcttgctcacttcaagaatgaagctgcagacc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate