Basic Information
VIS ID
TVIS10011174
Fusion event
HBV-chr12 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
660
Orient
-
Integrated sequence
CTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCC| |CGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGG
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
GRCh37/hg19
Start
95545/10193 (Hg38)
End
95545/10193 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Downstream/1650122;
Nearest TSS
ENST00000382841/Downstream/27909;
Nearest CpG islands
None/Target, None/Upstream, chr12-CpG: 104/Downstream/20596
Nearby gene
WASH8P(-4282) ; FAM138D(+52401) ;
Upstream sequence
ggttagggttaggggtagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttaggggt
Downstream sequence
tgggttggggtaggggtttgggttaggggttagggttagggttggggtagggttagggttagggttagggttagggttaaggttagggttagggttaggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate