VISDB Viral Integration Site DataBase

VIS ID

TVIS10011177

Fusion event

HBV-chr15 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1901

Orient

+

Integrated sequence

TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG| |CATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACC

Chromosome

chr15

Cytoband

q26.1

Reference genome

Start

End

90454089/89910857 (Hg38)

Orient

+

Location type

Intronic

Target gene

ARPIN ; ARPIN-AP3S2

miRNAs that regulate target gene

hsa-mir-6807-5p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6751-3p ; hsa-mir-769-5p ; hsa-mir-1199-5p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-4302 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4293 ; hsa-mir-449b-3p ; hsa-mir-508-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-6862-5p ; hsa-mir-3945 ; hsa-mir-4253 ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-4716-5p ; hsa-mir-3607-5p ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-18a-5p ; hsa-mir-548m ; hsa-mir-4786-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1247-3p ; hsa-mir-1247-3p ; hsa-mir-1292-3p ; hsa-mir-140-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-194-3p ; hsa-mir-2467-3p ; hsa-mir-2467-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-3612 ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-377-5p ; hsa-mir-377-5p ; hsa-mir-4257 ; hsa-mir-4257 ; hsa-mir-4453 ; hsa-mir-4537 ; hsa-mir-4538 ; hsa-mir-455-3p ; hsa-mir-455-3p ; hsa-mir-4640-5p ; hsa-mir-4726-5p ; hsa-mir-500a-3p ; hsa-mir-5186 ; hsa-mir-6086 ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6499-3p ; hsa-mir-6508-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6516-5p ; hsa-mir-6516-5p ; hsa-mir-6828-5p ; hsa-mir-767-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-1273e ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-6807-5p

Nearest miRNA

hsa-mir-10393/Upstream/26827; hsa-mir-1302-10/Downstream/95898;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/16495, chr15-CpG: 70/Downstream/1473

Upstream sequence

TGTCCAAGATGCTGTGCCGAGATACATCGATCAGTTCTCCCTCCAGCAGGACACCATTTCCCCTGGGGATGAAAGGGAAAGAAAGGATAGCCAGTTTTGT

Downstream sequence

CAGTCCTCAGCAAATCTCACCCGTGTCTCCTATTTACCCAGCCCTGAGAAGGCTGGGTACTGAGCAGCTCCTTTCCCCGTGCTTCCGACATAGGGATCTC