VISDB Viral Integration Site DataBase

VIS ID

TVIS10011182

Fusion event

HBV-GREB1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2755

Orient

-

Integrated sequence

TCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACAC| |ACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGG

Chromosome

chr18

Cytoband

q11.1

Reference genome

Start

End

18929616/21349655 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-4719 ; hsa-mir-5011-5p ; hsa-mir-4704-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485

Nearest miRNA

hsa-mir-3156-2/Upstream/6519413; hsa-mir-1-2/Downstream/333863;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/106267, chr18-CpG: 107/Downstream/250433

Upstream sequence

agccgtgggcaagcgagcattaccacctgagtgccacctcctgtcagatcagtggcggcattagattctcgtaggctcccaaaacctatcatgaactgtg

Downstream sequence

tgtgtgagggatctaggtcgcatgctccttatgagaatctaatgcctgatgatctgtcactgtcttccatcaccaccagatgggatcatctagttgcaga