Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011195
Fusion event
HBV-CTNND2 integration
Validated
Yes
Detection method
PCR and Sanger sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1495
Orient
-
Integrated sequence
CCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCT| |TCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCA
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
Start
End
11282976/11282864 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10397/Upstream/804719; hsa-mir-103a-1/Downstream/3543065;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/521051, chr5-CpG: 115/Downstream/101705
Nearest cancer related gene
CTNND2(OG, No orient, 0)
Upstream sequence
gaaaaaagttatggccaagaaatccaatatgtgatcttttttttaaatcttgtatcaaaagcaaacaggaaatacaaacatctatgaaacatattcagtg
Downstream sequence
ACCATCGCATACTGATATATCTTTGCCAGATAATGTTTACTCAAAACTCAGGAAACTCATGTTAAAACTTGCCTCGTTCTAGCACTCCCTCTTCCTCAGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.