VISDB Viral Integration Site DataBase

VIS ID

TVIS10011200

Fusion event

HBV-OXR1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

1934

Orient

-

Integrated sequence

GCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGC| |TACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCT

Chromosome

chr8

Cytoband

q23.1

Reference genome

Start

End

107565242/106553014 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-200b-3p ; hsa-mir-567 ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-4781-3p ; hsa-mir-144-3p ; hsa-mir-3144-3p ; hsa-mir-3915 ; hsa-mir-6730-3p ; hsa-mir-4689 ; hsa-mir-6858-5p ; hsa-mir-1224-5p ; hsa-mir-3928-3p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-586 ; hsa-mir-875-5p

Nearest miRNA

hsa-mir-12123/Upstream/2068549; hsa-mir-10400/Downstream/6090479;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/281366, chr8-CpG: 63/Downstream/104747

Upstream sequence

TAGCCATTAATATAACTTACACGAGGGGGCTGAGAATCTCTCTTGGTAAAATATTGAAACATGAGCTTCATGTCTTTTAAGAACTTTGTGGTTTATATCC

Downstream sequence

CAGTAGGATTTTATAAGTATTTGCCAGCATCTTAGGAAAGAAAATTTTTCTAAACCAAAGAGAGAAAAAAAATTGTAGGCATAaatgctaaatgatgagt