VISDB Viral Integration Site DataBase

VIS ID

TVIS10011216

Fusion event

HBV-SPRTN integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1737

Orient

-

Integrated sequence

TATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGA| |GGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCC

Chromosome

chr1

Cytoband

q42.2

Reference genome

Start

End

231483795/231348049 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-548b-3p ; hsa-mir-186-5p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-4470 ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-3128 ; hsa-mir-1278 ; hsa-mir-892b ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-1277-5p ; hsa-mir-3144-3p ; hsa-mir-5682 ; hsa-mir-1257 ; hsa-mir-31-5p ; hsa-mir-875-5p ; hsa-mir-6871-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-5586-3p ; hsa-mir-3910 ; hsa-mir-3714 ; hsa-mir-124-3p ; hsa-mir-506-3p ; hsa-mir-7152-5p ; hsa-mir-486-5p ; hsa-mir-545-3p ; hsa-mir-512-5p ; hsa-mir-4261 ; hsa-mir-3688-3p ; hsa-mir-7151-5p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-101-1/Upstream/328125; hsa-mir-1537/Downstream/2276103;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/9413, chr1-CpG: 172/Downstream/72886

Upstream sequence

GATGTTTAGTAGTTGTTTATTCAATAACTCCTGAGATTTAATTAAAAGTAGAGAACTAGGTAGAAACAAGTATCTTTGAGGATTTTCCACAGCGAACGAG

Downstream sequence

AGGCCTAGAGAAGCAAATTGGCTTGTCTGGGACTACATGGTGGAATGGCAGCAGAGCCAGTGATATCCCTGAGGCCTCTGACCTCTTCTGAGTCAACATT