Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011217
Fusion event
HBV-TSNAX-DISC1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1783
Orient
-
Integrated sequence
GTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGC| |TGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTG
Host Sequence
Chromosome
chr1
Cytoband
q42.2
Reference genome
End
232031346/231895600 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-101-1/Upstream/875676; hsa-mir-1537/Downstream/1728552;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/268231, chr1-CpG: 173/Downstream/733742
Upstream sequence
gtgttacagttgtcatacttttacttccacatatgttgtaaattcagatcaataaggttttaaaaattaaattattgttttctttcctgggataaactct
Downstream sequence
attattctttaccactgtgctagatttttttttttactaattcttaaagcatttttgcatccatattaataaatggaattaactgtaattttgtttcttc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.