Basic Information
VIS ID
TVIS10011218
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1817
Orient
-
Integrated sequence
TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
End
247862921/247699619 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/497559; hsa-mir-3124/Downstream/1126758;
Nearby gene
OR13G1(-26578) ; OR6F1(+12210) ;
Upstream sequence
ttttgagacagagttcgctcagtagcccaggctggagggcaatggcacgatctcagctcactgcaacctccacctcccgggttcaagcgattctcccatc
Downstream sequence
tcaacctcctgagtagctggaattacaggaacctgcaatcctgcctggctaatttttgtatttttagtagatacggggtttcaccatattggccaggctg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate