Basic Information
VIS ID
TVIS10011219
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1821
Orient
-
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
End
249240066/248945867 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/119424;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/39076, None/Downstream
Nearby gene
PGBD2(-26721) ;
Upstream sequence
ttagggttaggggttaggggttagggttagggttagggttaggggttaggggttaggggttagggttagggttagggttagggttgggttagggttaggg
Downstream sequence
ttagggttagggttaggggttagggttagggttgggttagggttagggttaggggttagggttaggggttagggttagggttagggttagggttagggtt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate