VISDB Viral Integration Site DataBase

VIS ID

TVIS10011224

Fusion event

HBV-C8A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1762

Orient

-

Integrated sequence

GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA| |AAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTAC

Chromosome

chr1

Cytoband

p32.2

Reference genome

Start

End

57333774/56868101 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-181a-5p ; hsa-mir-127-5p ; hsa-mir-1299 ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-4635 ; hsa-mir-4522 ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-518c-5p ; hsa-mir-514a-5p ; hsa-mir-4762-3p ; hsa-mir-4539 ; hsa-mir-766-3p ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-3065-3p ; hsa-mir-500b-3p ; hsa-mir-6871-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-3124-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-483-3p

Nearest miRNA

hsa-mir-12136/Upstream/1642378; hsa-mir-101-1/Downstream/2865126;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/222537, chr1-CpG: 222/Downstream/554190

Upstream sequence

ACTCATGAGGGTCTTCTGGAGGAAGTAATAGCTTAGAAACAAAATACAAAGCTGCCCATGAGGAGATGAGATAATCCAAGGGATATCCCAGAGTGTGTTC

Downstream sequence

TTGAGAATTCCACTTTCATATATTGAAAAGACCAACACACCCAATGAAGAGAGGTGTGTTTACTTTGCCTATCTAAATGGTTTTGAATAGTTCAAAATGA