Fusion event
HBV-PIK3CD integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
S protein|Polymerase|large S protein|middle S protein|
Integrated sequence
GAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGA| |TGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAAC
End
9699426/9639368 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12136/Upstream/487591; hsa-mir-101-1/Downstream/328013;
Upstream sequence
CTAGGTGCTTTTCAAGATAGAGGGCTAACTACCGAGAGTGGGTATTTATCTAGAGAGATAGAGGCTTTTGGAGCAGGAGCACCCTAGGTAGTGGTGGATG
Downstream sequence
GGGCAGGGCCCAGCTCCATCCTGCTGAGCACCCCCGAGAGGGTAACCTATTTGCAAAGCTTTTACTCGTCTCTAAACCACTTTTGCTAAAACGTCTATTT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.