Basic Information
VIS ID
TVIS10011240
Fusion event
HBV-LOC107984205 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1724
Orient
-
Integrated sequence
AACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGT| |TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT
Host Sequence
Chromosome
chr10
Cytoband
p14
Reference genome
GRCh37/hg19
Start
8250382/8208419 (Hg38)
End
8250382/8208419 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107984205
Nearest miRNA
hsa-mir-3155a/Upstream/2056142; hsa-mir-107/Downstream/3922341;
Nearest TSS
ENST00000439456/Upstream/150020; ENST00000413941/Downstream/52385;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/149614, chr10-CpG: 31/Downstream/305276
Nearby gene
GATA3(-133218) ;
Upstream sequence
ggaaggtcaaagaaggctttctagaggaggaaacatggtaagtgagtcttggctcagagaagttgagcgggTAGTATGCATATATCTGTCAGAGTAAGCC
Downstream sequence
ATAGGCTTAGAGTGGAGAAATATACAAGGACCCTCAAAcagaactcatgtgattgtaagtgacagaaactcaacgccacctagtttaagccaagaggcaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate