VISDB Viral Integration Site DataBase

VIS ID

TVIS10011241

Fusion event

HBV-PANK1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1721

Orient

-

Integrated sequence

GTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTT| |TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA

Chromosome

chr10

Cytoband

q23.31

Reference genome

Start

End

91403607/89643850 (Hg38)

Orient

-

Location type

UTR5

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-548c-3p ; hsa-mir-205-5p ; hsa-mir-4439 ; hsa-mir-6873-3p ; hsa-mir-3136-5p ; hsa-mir-452-3p ; hsa-mir-6895-3p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-3185 ; hsa-mir-6817-3p ; hsa-mir-345-5p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-3184-3p ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-6070 ; hsa-mir-670-5p ; hsa-mir-5195-3p ; hsa-mir-2115-5p ; hsa-mir-145-5p ; hsa-mir-4427 ; hsa-mir-3140-5p ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-2114-5p ; hsa-mir-1276 ; hsa-mir-4279 ; hsa-mir-6749-3p ; hsa-mir-642a-5p ; hsa-mir-4469 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-3927-5p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-767-5p ; hsa-mir-3130-3p ; hsa-mir-153-5p ; hsa-mir-329-5p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p

Nearest miRNA

hsa-mir-107/Upstream/51023; hsa-mir-1287/Downstream/6420465;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/107682, chr10-CpG: 99/Downstream/630

Upstream sequence

GTTGAATGAGCTTCAGTCAAGAAAAACCAGCTGTAAACTCGACCTACAAATTTACATCCCACAGCGTCCTGTGGGGAAGGTACACTTTACAAACTACCAT

Downstream sequence

TATATATACAAGCTTTAGATTGTGAAATAATGCACTTCGGCTTTCTCCGGTGTACATTACAATTACAAACCCTCAACTCAACCTCCCCCTTCGTTGAAAA