VISDB Viral Integration Site DataBase

VIS ID

TVIS10011243

Fusion event

HBV-ANO3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1687

Orient

-

Integrated sequence

TCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCA| |ACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTA

Chromosome

chr11

Cytoband

p14.2

Reference genome

Start

End

26499871/26478324 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-18a-3p ; hsa-mir-186-5p ; hsa-mir-26a-5p

Nearest miRNA

hsa-mir-210/Upstream/3059134; hsa-let-7a-2/Downstream/1036646;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/146059, chr11-CpG: 29/Downstream/884748

Upstream sequence

GATCTCTTTTCTGAAAAGCAAGAAAAAGTTTGGAGAGCCCCAGTATCTCATAACCTTGATCACATGTCTATTCTTTGCACTAAAACAAGATGAAAACAAC

Downstream sequence

AAATCACTCTAACCTAGAATAGCCTTTGTTTTCTGGCCCACTTTAGGTCAAAGAGATAAGAGACTTTACATATTGATGTAGAGATATATGGTGGATTTTT