Basic Information
VIS ID
TVIS10011244
Fusion event
HBV-chr11 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1782
Orient
-
Integrated sequence
TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG| |CTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGT
Host Sequence
Chromosome
chr11
Cytoband
p12
Reference genome
End
38116055/38094505 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1343/Upstream/2084301; hsa-let-7a-2/Downstream/5465151;
Nearby gene
C11orf74(-1435238) ;
Upstream sequence
TATTATTAAAAATAGTATATGTaggcagaagaatggcgtgaacccaggaggcagagcttgcagtgagccaagatggtaccactgcactccagcctgggcg
Downstream sequence
acagagcgagactctgtctcaaaaaaaaaacaaaacaaaaaacaaaaaaCTATATGTAATATTAGCTTGTATAAAATAATCAGAAAACAAGACAAATATC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate