Basic Information
VIS ID
TVIS10011257
Fusion event
HBV-LINC00571 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|large S protein|middle S protein|
Start
18
Orient
+
Integrated sequence
AATTCCACAACCTTCCAC| |CAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTAT
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
38679646/38105509 (Hg38)
End
38679646/38105509 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00571
Nearest miRNA
hsa-mir-2276/Upstream/13943005; hsa-mir-1267/Downstream/1558525;
Nearest TSS
ENST00000623511/Upstream/44056; ENST00000464423/Downstream/37723;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/235418, chr13-CpG: 32/Downstream/244311
Upstream sequence
gcaacttggaaaaaatatttgaggatattgttcaagaaaatttccccaaactcactagagaggtcaacattcaaattcaagaaattcagcaaagctctgg
Downstream sequence
gagacactatacaaaatgaccattcccaaggcaaatagtcatcagattcttaaaggtcagtgagtaagaaaaaaatatttaaggtagctagagagaaggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate