VISDB Viral Integration Site DataBase

VIS ID

TVIS10011260

Fusion event

HBV-KCNH5 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1726

Orient

-

Integrated sequence

CGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTT| |AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT

Chromosome

chr14

Cytoband

q23.2

Reference genome

Start

End

63237701/62770983 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-5704 ; hsa-mir-3926 ; hsa-mir-548o-3p ; hsa-mir-1295b-3p ; hsa-mir-1323 ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-5582-3p

Nearest miRNA

hsa-mir-208a/Upstream/2122272; hsa-mir-1185-1/Downstream/1324041;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/653422, chr14-CpG: 96/Downstream/274306

Upstream sequence

ccacccgcaaattcatatggggaagccttaacctctagtatggctgtatttggagacaaggcttctgagaaagtaatcaaggttacgtgaggtcataatg

Downstream sequence

atgaggctctgatccaataggacttgtgtctttataacaagagactcgagagctctctcactctctcacacacaggcactgcagggatgccatgtgagca