Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011266
Fusion event
HBV-ADAMTSL3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1740
Orient
-
Integrated sequence
TGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGA| |GTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAA
Host Sequence
Chromosome
chr15
Cytoband
q25.2
Reference genome
Start
End
84340493/83671741 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10393/Upstream/604326; hsa-mir-11181/Downstream/1708855;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/16722, chr15-CpG: 65/Downstream/408100
Upstream sequence
TTATATTCTCTGCATTGAAGAATATTGTTCTGCTGTCCCCGACTCTTCTTTACTAGttctctccctctgcttttgcactcccatactaattcccctttag
Downstream sequence
ctctagtggggagcaatctaactcttttgttttcttgtctcctattgatctgtgtccttaggagctctgccaacaaatgcttgcctagctgtttttgtaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.