VISDB Viral Integration Site DataBase

VIS ID

TVIS10011273

Fusion event

HBV-RANBP10 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2408

Orient

+

Integrated sequence

ATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCA| |ATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGT

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

67804427/67770524 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-330-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-15b-5p ; hsa-mir-222-3p ; hsa-mir-6510-5p ; hsa-mir-3175 ; hsa-mir-6864-5p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-3179 ; hsa-mir-7515 ; hsa-mir-873-3p ; hsa-mir-6857-3p ; hsa-mir-4499

Nearest miRNA

hsa-mir-1225/Upstream/568129; hsa-mir-11401/Downstream/462902;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/50981, chr16-CpG: 69/Downstream/35848

Upstream sequence

GAAATCAGTCTACTAGAAAAAAATCAGTGATTCACATTAAACATTGATTAGAAAAGACGTAAGGTCTGAGTGTAACTCCCTGTTTGGGGAAAGCCAGCTG

Downstream sequence

CCTTCTCTGTGTCATAGGCACAAAGAGCAGGAGGCCAAGAAAAAAACACAAGGACTTTTCCTGACCCCATGACGTGTCAGGGAAGCCTGGATCATGTCAC