Basic Information
VIS ID
TVIS10011283
Fusion event
HBV-chr18 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1828
Orient
+
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
End
62773501/65106265 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/6655107; hsa-mir-5011/Downstream/1975319;
Nearby gene
LINC01924(-682674) ; CDH7(+643987) ;
Upstream sequence
AATATATTGATAATAACATTGAGTTATATGTTACGTCTACACTGGCAAGAATTTGAAATGACAGTTGTGCTCAGAGGGTAACAAACCCTTGGGAGAATAG
Downstream sequence
AAAGAAACATGACTGCATTTTCAGTATATTTGCATATCCTCTAGGGCTTTTTCTATGTGGAATGACGTTTCCTTTGTTATTTTTCTTCTGAGAAAGATAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate