Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011290
Fusion event
HBV-ZNF304 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1811
Orient
-
Integrated sequence
AAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAG| |CACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATC
Host Sequence
Chromosome
chr19
Cytoband
q13.43
Reference genome
Start
End
57872038/57360670 (Hg38)
Orient
+
Location type
downstream
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7e/Upstream/1972428; hsa-mir-10394/Downstream/974018;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/8802, chr19-CpG: 31/Downstream/2719
Upstream sequence
gttttgaaatggagtcttgctctgttgcccaggctggagtacagtggcatgatttcggctcactgcaacctccacctcccgggttcaagcgattctccca
Downstream sequence
ccttagccttccaagcagctgggactacaggcacccgccaccatgcccagctaatttttgtatttttagcagaaatggggtttcgccatgttggccaggc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.