VISDB Viral Integration Site DataBase

VIS ID

TVIS10011292

Fusion event

HBV-RFX2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1805

Orient

-

Integrated sequence

TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

6100656/6100645 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-151b ; hsa-mir-151a-5p ; hsa-mir-611 ; hsa-mir-3131 ; hsa-mir-4695-5p ; hsa-mir-3150b-5p ; hsa-mir-3150a-5p

Nearest miRNA

hsa-mir-1227/Upstream/1167905; hsa-let-7e/Downstream/288993;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/60428, chr19-CpG: 22/Downstream/8165

Upstream sequence

CCAGTAAGAAGGACCAAGACTCCAGAGGCCACTGGCACTAGAATAAGAAGAGAAGTAGGCTCATGCAGGCCCACGTAAATCGGAGGAAGGTGGAAGTTTC

Downstream sequence

CTGACCGGAAGTCTAGGTGGGAGGCGCCATGTTGCGGCCCAGCCGCTGCTACTGACTCCACCATCCGGCAGTTCGTGAAATTAAATAACTGCAAATTGAT