Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011300
Fusion event
HBV-CALCRL integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|Core and e antigen|
Start
2285
Orient
+
Integrated sequence
TAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCAC| |TCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCC
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
End
188232175/187367448 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/2988404; hsa-mir-1244-1/Downstream/930044;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/518106, chr2-CpG: 106/Downstream/924241
Upstream sequence
TTAGTTTCTTCCATTTCTACCTCCAGGCACTGTGCAACTTAAACAAATGCAGACAGATGCTAAGTAACATATGGTTTCTATCAATGTCTAGTGTAAAAAT
Downstream sequence
GGCACTGATTTTTCTGATGATGCATATTGTTTCCTTCTAAACATATTCATTAACACATGTAAGTAGATTGGTACAAATAAAATCAACCTGTAAGTGAAAA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.