Basic Information
VIS ID
TVIS10011302
Fusion event
HBV-LINC00607 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1779
Orient
-
Integrated sequence
CAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGG| |AGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGC
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
216607557/215742834 (Hg38)
End
216607557/215742834 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00607
Nearest miRNA
hsa-mir-10b/Upstream/1984675; hsa-mir-1244-1/Downstream/2157679;
Nearest TSS
ENST00000437798/Upstream/24791; ENST00000443971/Downstream/84569;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/306697, chr2-CpG: 51/Downstream/270342
Upstream sequence
TAGTAAATAGGCACAGCTGTACACAAACCTTCTGCCTTGACCCAAGTGGGTCTTGGGCATTAACAGCAAAGATCCTCAGAAGAAATCTCCTTGGCactca
Downstream sequence
ggtacaagaaatatcacatgccttcattttctaaattaatatataattggctcaccccacacgtgccagttggtggagaatccagctacaatcattTTTC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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