VISDB Viral Integration Site DataBase

VIS ID

TVIS10011303

Fusion event

HBV-MYT1L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1805

Orient

-

Integrated sequence

TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG

Chromosome

chr2

Cytoband

p25.3

Reference genome

Start

End

2171573/2167801 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-7856-5p ; hsa-mir-4503 ; hsa-mir-6792-5p ; hsa-mir-501-5p

Nearest miRNA

hsa-mir-10b/Downstream/3806861;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/230013, chr2-CpG: 111/Downstream/17627

Upstream sequence

GGTAACTCTCCAGCCCTCCACGCCTTCTCCAGGAACACTCAGATTCTCCCCTTTGGGGTGGCTTCATCCTCCTGACTTTGCAGCTCCTTCTCCAGGTGTT

Downstream sequence

CTCTTGTTGTGGTTGTTGTTATACTCTCACCCTTATTAAATGGCTCAACAAGAACAGCTTTTCTGCAGAATTCTCTGATTCCATTTCTATATAACATCTG