VISDB Viral Integration Site DataBase

VIS ID

TVIS10011304

Fusion event

HBV-SH3BP4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1752

Orient

-

Integrated sequence

TACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGA| |GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT

Chromosome

chr2

Cytoband

q37.2

Reference genome

Start

End

235963394/235054750 (Hg38)

Orient

-

Location type

UTR3

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-7-5p ; hsa-mir-192-5p ; hsa-mir-106b-3p ; hsa-mir-193b-3p ; hsa-mir-93-5p ; hsa-mir-203a-3p ; hsa-mir-520g-3p ; hsa-mir-518a-5p ; hsa-mir-520h ; hsa-mir-527 ; hsa-mir-574-5p ; hsa-mir-595 ; hsa-mir-653-5p ; hsa-mir-3659 ; hsa-mir-4656 ; hsa-mir-4658 ; hsa-mir-6790-5p ; hsa-mir-8077 ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-4722-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6501-3p ; hsa-mir-6165 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-508-5p ; hsa-mir-7108-5p ; hsa-mir-644a ; hsa-mir-663b ; hsa-mir-4743-5p

Nearest miRNA

hsa-mir-10b/Upstream/2504177; hsa-mir-149/Downstream/2456181;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/11580, chr2-CpG: 22/Downstream/329906

Upstream sequence

GTGGTCCCTGCTGCTACGAGGCCATTGTACTGTTTTTTCCTTGAGGTCAAAGCAGTGCTTCCCATAGAGTTTGCTGCCTCTTCTGTGGACAGGAAGAAAA

Downstream sequence

CTTCATGACCGAATCAGAGCCTTGGTGGCCACTGACTCTCGTGCTTATTGCAGATGCTGTGGTTGGCCTCACAAGCAACGCCTTATGCTGATGTGCAGAG