Basic Information
VIS ID
TVIS10011310
Fusion event
HBV-LINC01793 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
398
Orient
+
Integrated sequence
GTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTAT| |CATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCA
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
59462838/59235703 (Hg38)
End
59462838/59235703 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LINC01793
Nearest miRNA
hsa-mir-1301/Upstream/3234908; hsa-mir-10b/Downstream/1151659;
Nearest TSS
ENST00000437798/Upstream/17995; ENST00000415159/Downstream/13808;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/806726, chr2-CpG: 103/Downstream/1224984
Nearby gene
MIR4432(+1151659) ;
Upstream sequence
aggctagaagtccaaaagcaaggggtcagcagggctgcactccatccaaagactctagggtagaaactcccttgcctcttcctagcttctgtggttgctg
Downstream sequence
agaatccctggcatcccttgtctgatagctacgtcactcgaatttctgcctccatccccagatgaccctcttcccttgtgtgtgtctctggttctgtttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate