VISDB Viral Integration Site DataBase

VIS ID

TVIS10011311

Fusion event

HBV-chr2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2736

Orient

+

Integrated sequence

TTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCA| |AACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAA

Chromosome

chr2

Cytoband

p14

Reference genome

Start

End

68384966/68157834 (Hg38)

Orient

+

Location type

upstream

Fragile sites / regions

Target gene

PNO1 ; WDR92

miRNAs that regulate target gene

hsa-mir-142-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-7151-3p ; hsa-mir-6807-5p ; hsa-mir-5095 ; hsa-mir-6849-3p ; hsa-mir-4433a-3p ; hsa-mir-6504-3p ; hsa-mir-4433b-3p ; hsa-mir-4700-3p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-498 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-1264 ; hsa-mir-8070 ; hsa-mir-6778-3p ; hsa-mir-4679 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-5697 ; hsa-mir-562 ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-186-3p ; hsa-mir-4762-5p ; hsa-mir-5588-3p ; hsa-mir-6507-3p ; hsa-mir-4762-3p ; hsa-mir-6843-3p ; hsa-mir-6848-3p ; hsa-mir-640 ; hsa-mir-3192-3p ; hsa-mir-378a-5p ; hsa-mir-1193 ; hsa-mir-6759-3p ; hsa-mir-3151-3p ; hsa-mir-1237-3p ; hsa-mir-2392 ; hsa-mir-335-3p ; hsa-mir-3613-3p ; hsa-mir-4662a-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-1281 ; hsa-mir-4485-5p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6890-3p ; hsa-mir-122-3p ; hsa-mir-500a-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4487 ; hsa-mir-1827 ; hsa-mir-558 ; hsa-mir-5186 ; hsa-mir-3160-3p ; hsa-mir-17-3p ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-17-5p ; hsa-mir-186-3p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-302e ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-4731-5p ; hsa-mir-5089-5p ; hsa-mir-512-3p ; hsa-mir-519d-3p ; hsa-mir-520a-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-520e ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-526b-3p ; hsa-mir-5589-5p ; hsa-mir-619-5p ; hsa-mir-6506-5p ; hsa-mir-93-5p

Nearest miRNA

hsa-mir-1301/Upstream/1799506; hsa-mir-10b/Downstream/945848;

Nearest TSS

Nearest CpG islands

chr2-CpG: 70/Target, None/Upstream, None/Downstream

Upstream sequence

GGAGTGAGCCCAAGACCATCAGGCATATCTTAGGACAGCCTAACCCCGTTTTCCCCCCCACCGGCCCCAAATCCTGCAGGTCCCCGGCCTGTGACGTTTT

Downstream sequence

AGGAAAGGGGCGGAGCTGCAGGGGTGGTTGGCTGAGGCTGGCTTCTGCGTGGTGCAGCTGCGCACGTGTTTCAGCCGGCAGCGCTTTAAGATTTCCGGGG