VISDB Viral Integration Site DataBase

VIS ID

TVIS10011315

Fusion event

HBV-GGA1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1776

Orient

+

Integrated sequence

CAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACT| |AGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCA

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

38023691/37627684 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-320a ; hsa-mir-136-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-210-5p ; hsa-mir-4749-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-3667-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6756-3p ; hsa-mir-3127-3p

Nearest miRNA

hsa-mir-1286/Upstream/1340777; hsa-let-7a-3/Downstream/216588;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/18420, chr22-CpG: 51/Downstream/11659

Upstream sequence

CCTGAGGGGCAGTGGGTGGGGAAGTACTGCAGGGCCACCAGCCCCCAGCCAGCAGCTGCAGCACCACCTCCACAAGAGAAGCGAGATGCAGCCGCACTTC

Downstream sequence

CTGTCCCCGCACTGCACTGGCATAGTTCTGAGCCACCAGCTTCCTTCTGTTTTCCTCTCAGAGGCAAAGCATGGGGGCACAGGAGCCGGAAGTGCCAGGG