VISDB Viral Integration Site DataBase

VIS ID

TVIS10011326

Fusion event

HBV-CADPS integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1739

Orient

-

Integrated sequence

TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGG| |AGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTA

Chromosome

chr3

Cytoband

p14.2

Reference genome

Start

End

62596734/62611059 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-5096 ; hsa-mir-377-3p ; hsa-mir-4643 ; hsa-mir-8485 ; hsa-mir-8064 ; hsa-mir-335-3p ; hsa-mir-561-3p

Nearest miRNA

hsa-let-7g/Upstream/1993189; hsa-mir-12124/Downstream/4614405;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/232418, chr3-CpG: 127/Downstream/262883

Upstream sequence

gtattgtgactgacaaaaaattttttcttttaaaaatacattgaaatatttacaagtgaaatgttataacttggacttgcttcaacataatacagcacaa

Downstream sequence

tccagcccaaaatgtcagtagcactgaagctgagaaatcctgGTCAGCACTGACCACCCCACtgtctcataggcaccccacataacactcggcttctgat