VISDB Viral Integration Site DataBase

VIS ID

TVIS10011339

Fusion event

HBV-UGT2B10 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1810

Orient

+

Integrated sequence

CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT

Chromosome

chr4

Cytoband

q13.2

Reference genome

Start

End

69683813/68818095 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-133a-3p ; hsa-mir-7977 ; hsa-mir-500a-3p ; hsa-mir-4281 ; hsa-mir-6804-3p ; hsa-mir-5690 ; hsa-mir-502-3p ; hsa-mir-501-3p ; hsa-mir-890

Nearest miRNA

hsa-mir-12113/Upstream/2541167; hsa-mir-1243/Downstream/7755473;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/467892, chr4-CpG: 55/Downstream/1870042

Nearby gene

UGT2B15(-147319) ; UGT2A3(+110364) ;

Upstream sequence

GGAAAGTTTTAACGTTGTGTTTGTCTTTGCTTTTTTGAAGAGAAAAAGAACAAAATCAACAACAAAAAACCCAAAATTTGGTCTGGCCACCACGGAGCAC

Downstream sequence

TTTTAAATTTCCTCATCCATTCTTACCAAATGTTGATTTTGTTGGAGGACTCCACTGCAAACCTGCCAAACCCCTACCTAAGGTAAACATACTTTCGTTG