Basic Information
VIS ID
TVIS10011358
Fusion event
HBV-chr6 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2764
Orient
+
Integrated sequence
TACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGG| |AAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTT
Host Sequence
Chromosome
chr6
Cytoband
q16.3
Reference genome
End
103725348/103277473 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/4152777; hsa-mir-1202/Downstream/3506652;
Nearby gene
GRIK2(-1207390) ; HACE1(+1450620) ;
Nearest cancer related gene
HACE1(TSG, +1450620) ;
Upstream sequence
CAAGTGTGGCTGTCAGCAATATCAAGCAACACCTCAGATGTGCTATTATCTGAAGTGATATCAGACACTGTCAAGATCCAAATTTTCTAGGCTTCTCTCt
Downstream sequence
ggctgcctgtgattggctgaaccctgcctgtttgtgattagctgaagctcggctgttttttggagacttaaatcaggttttggtttgtttatgtattaag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate