VISDB Viral Integration Site DataBase

VIS ID

TVIS10011362

Fusion event

HBV-PCMT1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1768

Orient

-

Integrated sequence

TGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTC| |TTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCA

Chromosome

chr6

Cytoband

q25.1

Reference genome

Start

End

150076733/149755597 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-106b-3p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-330-3p ; hsa-mir-508-3p ; hsa-mir-570-5p ; hsa-mir-646 ; hsa-mir-3135a ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-4477b ; hsa-mir-7856-5p ; hsa-mir-548ba ; hsa-mir-4445-5p ; hsa-mir-1283 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-219a-5p ; hsa-mir-6766-3p ; hsa-mir-4782-3p

Nearest miRNA

hsa-mir-10398/Upstream/9071714; hsa-mir-1202/Downstream/1347078;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/5448, chr6-CpG: 167/Downstream/107611

Upstream sequence

tcttggaggagaacaaaccagaaagagaatgagggaagaacattctatacagatgaaagaaatggaacaaagacatgaaataaactgggcatggttTATT

Downstream sequence

TTCAGTCCATTCCCCTAATGATCAATTGTTTCTACTTATGTTTCTTTTGCATTCTTGATTTTGTCATTTTACATATATAATGTTTATGGAATTTGtcatt