VISDB Viral Integration Site DataBase

VIS ID

TVIS10011368

Fusion event

HBV-RREB1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1809

Orient

-

Integrated sequence

TCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACC| |AGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACA

Chromosome

chr6

Cytoband

p24.3

Reference genome

Start

End

7203125/7202892 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-671-5p ; hsa-mir-106b-5p ; hsa-mir-30d-5p ; hsa-mir-145-5p ; hsa-mir-143-3p ; hsa-mir-889-3p ; hsa-mir-3653-3p ; hsa-mir-3658 ; hsa-mir-224-3p ; hsa-mir-137 ; hsa-mir-522-3p ; hsa-mir-4694-3p ; hsa-mir-4729 ; hsa-mir-485-3p ; hsa-mir-539-3p ; hsa-mir-582-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-5195-5p ; hsa-mir-545-5p ; hsa-mir-548t-3p ; hsa-mir-3150a-5p ; hsa-mir-3150b-5p ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548at-3p ; hsa-mir-548ay-3p ; hsa-mir-582-3p ; hsa-mir-548c-3p ; hsa-mir-4719 ; hsa-mir-218-5p ; hsa-mir-510-3p ; hsa-mir-431-5p ; hsa-mir-4764-5p ; hsa-mir-4738-3p ; hsa-mir-4635 ; hsa-mir-6507-5p ; hsa-mir-6782-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-513a-5p ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-608 ; hsa-mir-7110-5p ; hsa-mir-4651 ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-3202 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-27a-3p ; hsa-mir-3681-3p ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-27b-3p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-4684-5p ; hsa-mir-942-5p ; hsa-mir-599 ; hsa-mir-3143 ; hsa-mir-5087 ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-589-3p ; hsa-mir-410-3p ; hsa-mir-4773 ; hsa-mir-543 ; hsa-mir-101-3p ; hsa-mir-139-5p ; hsa-mir-3675-3p ; hsa-mir-144-3p ; hsa-mir-5692a ; hsa-mir-6801-5p ; hsa-mir-1178-5p ; hsa-mir-3912-3p ; hsa-mir-6873-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-1304-3p ; hsa-mir-483-3p ; hsa-mir-421 ; hsa-mir-4709-5p ; hsa-mir-1976 ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-450a-1-3p ; hsa-mir-4776-5p ; hsa-mir-6772-3p ; hsa-mir-4303 ; hsa-mir-3619-3p ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-591 ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-301b-5p ; hsa-mir-301a-5p ; hsa-mir-146a-3p ; hsa-mir-4254 ; hsa-mir-3690 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6892-3p ; hsa-mir-6865-3p

Nearest miRNA

hsa-mir-3691/Upstream/1033457; hsa-mir-10398/Downstream/3236825;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/61549, chr6-CpG: 91/Downstream/26752

Upstream sequence

tggtaggagggagagatcatggatgtgaggtcaggaagggggttgtggacagatgctgaagcactgtgaaaatgggtcttctctactttgcagacagaga

Downstream sequence

CTTCTGAGGTCTTTTGTTTGTTTTTAAGAATGTCTGACTTTGTATGGACATATTACTATGTATTTTTGTGGATTTTGTAAATAGATATGGGGACCAAATA