Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10011377
Fusion event
HBV-SLC30A8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1801
Orient
-
Integrated sequence
GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG
Host Sequence
Chromosome
chr8
Cytoband
q24.11
Reference genome
End
118141356/117129117 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12123/Upstream/254317; hsa-mir-10400/Downstream/2196054;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/190397, chr8-CpG: 45/Downstream/391499
Upstream sequence
tccagtcttcttgagtgatatctctggatgtgggagtgaaccaaatgaatagcgcctgaagcgaacccctagcaaaccacagcagccctacagaggaggg
Downstream sequence
CCAGCAAGGAGTTTCAGTTAGTAGCTAATGACTATGTTGAATAAAAGTAGAATGCTCCAGGACTTTTCATCTGGCCAGTTAGCACTGCAATGGATGTGTT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.