VISDB Viral Integration Site DataBase

VIS ID

TVIS10011379

Fusion event

HBV-GPAT4 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1818

Orient

+

Integrated sequence

GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT

Chromosome

chr8

Cytoband

p11.21

Reference genome

Start

End

41447114/41589595 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-1226-3p ; hsa-mir-423-5p ; hsa-mir-149-5p ; hsa-mir-1260b ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-4697-5p ; hsa-mir-4488 ; hsa-mir-1237-5p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-4467 ; hsa-mir-8072 ; hsa-mir-3960 ; hsa-mir-766-3p ; hsa-mir-4267 ; hsa-mir-194-3p ; hsa-mir-1296-3p ; hsa-mir-4519 ; hsa-mir-508-5p ; hsa-mir-3178 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4486 ; hsa-mir-5693 ; hsa-mir-6071 ; hsa-mir-3156-3p ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-3692-5p ; hsa-mir-93-3p ; hsa-mir-4301 ; hsa-mir-4661-5p ; hsa-mir-203b-3p ; hsa-mir-670-5p ; hsa-mir-1260a ; hsa-mir-4539 ; hsa-mir-7113-3p ; hsa-mir-532-3p ; hsa-mir-4319 ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-4732-3p ; hsa-mir-345-3p ; hsa-mir-1224-3p ; hsa-mir-483-3p ; hsa-let-7a-5p ; hsa-let-7b-5p ; hsa-let-7c-5p ; hsa-let-7d-5p ; hsa-let-7e-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-1247-3p ; hsa-mir-1343-3p ; hsa-mir-1343-5p ; hsa-mir-2278 ; hsa-mir-3160-3p ; hsa-mir-377-5p ; hsa-mir-3927-3p ; hsa-mir-3940-3p ; hsa-mir-4451 ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-450b-3p ; hsa-mir-4532 ; hsa-mir-455-3p ; hsa-mir-4633-3p ; hsa-mir-4713-3p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-6086 ; hsa-mir-619-5p ; hsa-mir-638 ; hsa-mir-6499-3p ; hsa-mir-6500-5p ; hsa-mir-6501-3p ; hsa-mir-6506-5p ; hsa-mir-6516-5p ; hsa-mir-6742-3p ; hsa-mir-6777-5p ; hsa-mir-6783-3p ; hsa-mir-6799-5p ; hsa-mir-6831-5p ; hsa-mir-6838-3p ; hsa-mir-6852-5p ; hsa-mir-6874-5p ; hsa-mir-6889-5p ; hsa-mir-769-3p ; hsa-mir-939-3p ; hsa-mir-939-5p ; hsa-mir-98-5p

Nearest miRNA

hsa-mir-124-1/Upstream/318452; hsa-mir-10400/Downstream/70846;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/10955, chr8-CpG: 38/Downstream/56802

Nearest cancer related gene

GPAT4(OG, No orient, 0)

Upstream sequence

cacaccactgcactccagcctgggtaacagagtgagactctgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaagtg

Downstream sequence

gtgaaaaagactgtagccagatgtgggctgtgactggccaacccctgAACTAGGTGAAGAAATTGGTTTATTGCTGCAGGTGTTTACTGGTTTGGGGACA