VISDB Viral Integration Site DataBase

VIS ID

TVIS10011380

Fusion event

HBV-SNTG1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2185

Orient

-

Integrated sequence

TGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCC| |TAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCAC

Chromosome

chr8

Cytoband

q11.21

Reference genome

Start

End

51517502/50604942 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-2681-5p ; hsa-mir-548c-3p ; hsa-mir-7977 ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-3671 ; hsa-mir-6849-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p

Nearest miRNA

hsa-mir-124-1/Upstream/7708667; hsa-mir-10400/Downstream/11109846;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/694642, chr8-CpG: 98/Downstream/803660

Upstream sequence

gaggtggaggctgcagtgagctgagatcatgccactgcactccagcctgggcaacagagtgagactctgtctcaaaaaaaaaaaaaaaaaaaaaaaaaaa

Downstream sequence

ttctttagtcagcaggtgatgaattgtccccagactgggtccctcccttcaaggcagtgggtttccttctggcccaaggtgtatctagaaatgtctagga