Basic Information
VIS ID
TVIS10011387
Fusion event
HBV-chr8 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2584
Orient
-
Integrated sequence
TACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGT| |GAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGG
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
78200305/77288069 (Hg38)
End
78200305/77288069 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/321219; hsa-mir-10400/Downstream/2044119;
Nearest TSS
ENST00000518652/Upstream/287025; ENST00000524014/Downstream/111003;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/287248, chr8-CpG: 46/Downstream/1228129
Nearby gene
PEX2(-287025) ; PKIA(+1228031) ;
Upstream sequence
ATAGATGGGTAGAGACCACATCAGTCTATAATGCAGAATAAATTATGTTAGTGAAATCTCTATGGGCTTTTGATTATTATATAATTTATTGATGTTTTCC
Downstream sequence
tccacttctccacatacctcattcctcctggacactggacaagaactcaggacctgccaaatggcagggctaaaagagctgtaacacaaacagagctgaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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