VISDB Viral Integration Site DataBase

VIS ID

TVIS10011390

Fusion event

HBV-ERI1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1847

Orient

+

Integrated sequence

GAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTC| |TTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTA

Chromosome

chr8

Cytoband

p23.1

Reference genome

Start

End

8830450/8972940 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-30c-5p ; hsa-mir-548p ; hsa-mir-1277-5p ; hsa-mir-6507-5p ; hsa-mir-186-5p ; hsa-mir-208a-3p ; hsa-mir-6888-3p ; hsa-mir-3120-5p ; hsa-mir-6868-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-3664-5p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-4724-3p ; hsa-mir-20a-3p

Nearest miRNA

hsa-mir-3674/Upstream/883851; hsa-mir-10400/Downstream/75505;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/9338, chr8-CpG: 63/Downstream/29750

Nearby gene

MFHAS1(-79319) ; ERI1(+29864) ;

Upstream sequence

catggtgaaaccccatctctactgaaaatacaaaaaattagccaggcgtggtggtgggcgcctgtagtcccagctgcttgggaagctgaggcaggagaat

Downstream sequence

atcattttatatttGCTGAGAGCTTTTCCTTTGAACATAGATTGGGGGAGGCAGTTTCATGGATTTCCATGTTCATAACTGGATCTGTCCCCAGTCTTTT