VISDB Viral Integration Site DataBase

VIS ID

TVIS10011395

Fusion event

HBV-GLIS3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1780

Orient

-

Integrated sequence

AATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGA| |GGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCT

Chromosome

chr9

Cytoband

p24.2

Reference genome

Start

End

3984110/3984110 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-203a-3p ; hsa-mir-539-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-2355-3p ; hsa-mir-7159-3p ; hsa-mir-4482-3p ; hsa-mir-3679-3p ; hsa-mir-676-3p ; hsa-mir-431-5p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-138-2-3p ; hsa-mir-3655 ; hsa-mir-3667-3p ; hsa-mir-6734-3p

Nearest miRNA

hsa-mir-1302-9/Upstream/3953829; hsa-let-7a-1/Downstream/866187;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/457165, chr9-CpG: 69/Downstream/133715

Upstream sequence

TATAAAAGTTGCATAAACAGGAAAGATTATACAAATATACCATAAAAAGTACTTATAATAAAAATATGAGAAAAATACAAACTGATATGTAAACTATAAA

Downstream sequence

tgcagaagggaaaggtgatgttggagcccccacacaaagtccctcctagggcaccacttagcagagttgtgagaagatggtcattgtcctccagacccca