VISDB Viral Integration Site DataBase

VIS ID

TVIS10011429

Fusion event

HBV-QPCT integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1827

Orient

-

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT

Chromosome

chr2

Cytoband

p22.2

Reference genome

Start

End

37598606/37371463 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-7854-3p ; hsa-mir-10a-5p ; hsa-mir-10b-5p ; hsa-mir-1273g-3p ; hsa-mir-4252 ; hsa-mir-4293 ; hsa-mir-4725-5p ; hsa-mir-4786-5p ; hsa-mir-4793-3p ; hsa-mir-4797-5p ; hsa-mir-508-5p ; hsa-mir-5586-3p ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-759 ; hsa-mir-766-3p ; hsa-mir-769-5p ; hsa-mir-7703

Nearest miRNA

hsa-mir-1301/Upstream/1899977; hsa-mir-10b/Downstream/10006212;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/26209, chr2-CpG: 167/Downstream/299536

Upstream sequence

TAAGAGAAAgcagtgagctgaggtggcgccactgcactccagcctgggcgacagcgagactccatctcaaaaaaaaaaaaaaaaaaaaagaaaaaGTTGT

Downstream sequence

GTCTCATGGTAAAGGAATTATAAGTATCAATAAACAGACAAGAATATTGTTTTTGGTGGTAGTTAGGGCTTTCTCAATGTTTCTAGAATCATATTACATA