VISDB Viral Integration Site DataBase

VIS ID

TVIS10011437

Fusion event

HBV-EYS integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1827

Orient

-

Integrated sequence

AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT| |CACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAAT

Chromosome

chr6

Cytoband

q12

Reference genome

Start

End

64647234/63937341 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-510-3p ; hsa-mir-376a-5p ; hsa-mir-4680-5p ; hsa-mir-494-3p

Nearest miRNA

hsa-mir-10398/Upstream/6547129; hsa-mir-10524/Downstream/7439619;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/300781, chr6-CpG: 22/Downstream/1364019

Upstream sequence

gaggacagatcatgaggtcaggagttcaagaccagcctgaccaatatggtgaaaccccgtctctactaaaaatacaaaaattagctgggtgtggtggcac

Downstream sequence

tttctttttttttttttttttttttttttttttttttttttttttttttttttttttgagacggagtctcactttgttgcccaggctggagtgcagtggc