Basic Information
VIS ID
TVIS10011440
Fusion event
HBV-LINC00824 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|Polymerase|
Start
1621
Orient
+
Integrated sequence
CGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACC| |GTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTT
Host Sequence
Chromosome
chr8
Cytoband
q24.21
Reference genome
End
129524908/128512662 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1204/Upstream/362474; hsa-mir-10400/Downstream/971395;
Nearby gene
MIR1208(-362474) ; LINC00977(+703805) ;
Upstream sequence
AAATGTTAAATCAGGTTCTCTTGATCATTATGTATGTATTAAACCCTTGGAAACACACAGGGAAAGCTAAGACTCCTATCAGTTTCAGTGTTCAATACAT
Downstream sequence
TCTGCTTTTCCCCACTTTCTAGAACACTGTGCAAAAATAGAGGCACTGTCTGGTTGATTATATACCTCATTTGCCAGTCCTGGTAAATTGGACTGTCTGA
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate