VISDB Viral Integration Site DataBase

VIS ID

TVIS10011452

Fusion event

HBV-SERPINC1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2076

Orient

+

Integrated sequence

TTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCA| |ATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTA

Chromosome

chr1

Cytoband

q25.1

Reference genome

Start

End

173881422/173912284 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6865-3p ; hsa-mir-4446-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-3124-3p ; hsa-mir-130b-5p ; hsa-mir-1306-5p ; hsa-mir-6741-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-934 ; hsa-mir-3618 ; hsa-mir-4687-3p ; hsa-mir-7974 ; hsa-mir-6876-3p ; hsa-mir-626 ; hsa-mir-6504-5p ; hsa-mir-3064-5p ; hsa-mir-149-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-6812-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-181c-3p

Nearest miRNA

hsa-mir-101-1/Upstream/1767640; hsa-mir-1182/Downstream/2056086;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/43505, chr1-CpG: 93/Downstream/109383

Upstream sequence

AGGATAAAAGAAGAATGAAGGGTAGGAAGGATAAAGGGAAAAAGAGAGACTAGGTTGCCACCTAAAGTCTCTAAACGCCTCTAGATCAACACACAGACGT

Downstream sequence

TTTCTTGCTGGAATGGGAAAAGTCCTCTTGGTGATTCTGGACAGAGAAGAGAATCAGGACGGTGTCCTTCTCGTAACAAACACTTTTGTGGCATCTACTG